Paediatrics · ¹²³I-mIBG · Advanced

Abdominal mass and limp in a 3-year-old girl

History

3-year-old girl with 4 weeks of limp and irritability and a left upper quadrant mass. CT: 6 cm calcified left adrenal mass. Urinary catecholamine metabolites raised; biopsy: neuroblastoma, MYCN amplified; bone-marrow aspirates infiltrated. Staging ¹²³I-mIBG requested (thyroid blocked).

Step 1 · Staging scan

Simulated ¹²³I-mIBG anterior and posterior whole-body images at 24 h, at diagnosis.

What is the SIOPEN skeletal score?