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606 matching questions · page 1 of 51

Symmetric FDG uptake in the supraclavicular & paraspinal fat on a cold day.
Answer

Physiological

Reasoning

Brown adipose tissue — classic symmetric physiological FDG uptake; warming/beta-blockade reduces it.

Intense, symmetric salivary and lacrimal gland uptake on ⁶⁸Ga-PSMA PET.
Answer

Physiological

Reasoning

Salivary/lacrimal glands physiologically express PSMA — a normal finding, not disease.

Linear tracer activity along both ureters on ⁶⁸Ga-PSMA PET.
Answer

Physiological

Reasoning

Urinary excretion of the tracer — physiological; do not mistake for nodal disease.

Focal ⁶⁸Ga-PSMA uptake near the coeliac axis with no CT correlate.
Answer

Benign mimic

Reasoning

Coeliac (and other sympathetic) ganglia take up PSMA — a benign mimic of a nodal metastasis.

Photopenic defect with surrounding streak next to a metallic hip prosthesis.
Answer

Artefact

Reasoning

Attenuation-correction / metal artefact — check the non-attenuation-corrected images.

Apparent lung-base uptake that shifts position between AC and non-AC images.
Answer

Artefact

Reasoning

Respiratory misregistration artefact between PET and CT — not a true lesion.

Intense diffuse myocardial FDG uptake in a non-fasting patient.
Answer

Physiological

Reasoning

Physiological myocardial glucose use when inadequately fasted — prep-dependent, not disease.

Focal intense FDG uptake in the sigmoid colon matching a CT polyp.
Answer

Disease

Reasoning

Focal colonic FDG warrants colonoscopy — premalignant/malignant until proven otherwise.

On a ⁹⁹ᵐTc-MDP bone scan: uptake in stomach, thyroid and salivary glands.
Answer

Artefact

Reasoning

Free ⁹⁹ᵐTc-pertechnetate (radiopharmaceutical impurity) — a preparation artefact.

Symmetric bilateral vocal-cord / muscle FDG uptake after the patient talked.
Answer

Physiological

Reasoning

Physiological muscle uptake (phonation) — symmetric and activity-related.

Focal uptake at the antecubital injection site with ipsilateral axillary nodes.
Answer

Artefact

Reasoning

Extravasation artefact — tracer drains to axillary nodes; can mimic disease.

Diffuse increased FDG uptake throughout the thyroid gland.
Answer

Benign mimic

Reasoning

Usually chronic (Hashimoto) thyroiditis — a benign mimic; focal uptake is the one that needs work-up.