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Short read · Musculoskeletal

The Honda Sign on Bone Scan

Musculoskeletal · 1 min read

The Honda sign — also called the butterfly or H sign — is a characteristic pattern of increased tracer uptake in the sacrum on bone scan, seen in a sacral insufficiency fracture. It is increased activity in both sacral ala, the two vertical limbs, joined by a horizontal component across the sacral body, resembling the letter H or the Honda car logo.

Underlying pathology

  • Bilateral vertical sacral ala fractures with a transverse component.
  • Insufficiency fractures — weakened bone failing under normal stress.

Typical clinical context

  • Postmenopausal osteoporosis — the commonest setting.
  • Prior pelvic radiotherapy.
  • Long-term corticosteroid therapy; rheumatoid arthritis; renal osteodystrophy.

Why it matters

  • It explains low back or buttock pain that may otherwise be mistaken for metastasis, and spares the patient an unnecessary work-up.
  • Bone scan, with SPECT/CT where available, is very sensitive and may be positive before radiographs.
  • The complete H is not always present — partial patterns occur.

Fuller version, with the rest of benign bone disease: Metabolic & benign bone disease.

Take home
  • An H or butterfly of sacral uptake is a sacral insufficiency fracture, not metastasis.
  • Look for it in postmenopausal osteoporosis, after pelvic radiotherapy, and on long-term corticosteroids.
  • A partial pattern still counts — the complete H is often absent, and the scan may be positive before radiographs.
Sources
  1. Ries T. Detection of osteoporotic sacral fractures with radionuclides. Radiology. 1983;146(3):783-5.
  2. Lyders EM, Whitlow CT, Baker MD, Morris PP. Imaging and treatment of sacral insufficiency fractures. AJNR Am J Neuroradiol. 2010;31(2):201-10.
  3. Van den Wyngaert T, Strobel K, Kampen WU, et al. The EANM practice guidelines for bone scintigraphy. Eur J Nucl Med Mol Imaging. 2016;43(9):1723-38.